Hull City beat Albion 2-0 in the Sky Bet Championship on Friday evening.
Goals either side of half-time by Benjamin Tetteh and Sean McLoughlin earned the Tigers all three points at the MKM Stadium.
The Baggies have a chance to bound back on Tuesday when Wigan Athletic visit The Hawthorns (ko 8pm).
Carlos Corberán made one change to his starting XI, bringing Marc Albrighton in for the injured Grady Diangana.
And Albion began brightly, forcing Karl Darlow into a number of good saves early on to deny Albrighton’s strike, a low Jed Wallace shot and Daryl Dike’s goal-bound header.
However, against the run of play it was Hull who grabbed the opener – Tetteh finding the top corner via a powerful finish and ensuring the Baggies were behind at the break.
Despite Dike almost equalising straight after the restart - Darlow again denying him - Hull were the ones to push on and net a second when McLoughlin powered home with just over half-hour to go.
Albion tried to get back in it but were denied by a mixture of the woodwork and Darlow, as John Swift’s excellent free-kick struck the post and the hosts’ goalkeeper kept out Wallace and Adam Reach efforts.
Rico Richards came on for his Albion league debut 10 minutes from time in a bright moment for the club’s Academy.
Ultimately, though, Hull held their lead until full-time to claim the victory and leave Corberán’s side empty handed.
Albion: Griffiths; Furlong (Chalobah 58), O’Shea, Pieters (Richards 80), Townsend (Reach 65); Molumby (Gardner-Hickman 65), Yokuslu; Wallace, Swift, Albrighton; Dike.
Substitutes: Button, Ajayi, Malcolm.