Robson-Kanu, Nyom, Roberts and Field also in action
scored the third goal of his FIFA World Cup qualifying campaign as the Republic of Ireland recorded a precious 1-0 win over Austria in Vienna.
The Albion midfielder, who was handed the man of the match award, was on target for the second game in a row having also bagged a brace in his side's victory against Moldova last month.
McClean was given a standing ovation after being substituted in the 87th minute, with his second-half strike putting Martin O'Neill's men top of Group D with 10 points from four games.
Hal Robson-Kanu played 68 minutes for Wales and claimed a crucial assist in their 1-1 draw against Serbia in Cardiff.
Great work from the Baggies forward set up Gareth Bale for his first-half opener but Wales were ultimately left disappointed after the visitors snatched a late leveller to leave Chris Coleman's side with just a point from the qualifier.
Wales sit third in Group D behind both Serbia and the Republic of Ireland.
Allan Nyom was also in action as his Cameroon side were held to a 1-1 draw at home to Zambia in a World Cup qualifying match.
That is the second draw of the Indomitable Lions' campaign after finishing 1-1 in Algeria last time out.
There were mixed emotions for Baggies youngsters Sam Field and Tyler Roberts as England's Under-19 side came up against Wales in Bangor.
Roberts captained the Young Dragons to a 3-2 victory, while Field was an unused substitute for Keith Downing's side.